WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00107847 Genotype  gld-1(q485)
Phenotype Remark  "(tumor cell) Invasion of the vulva region often results in the appearance of a tumor prolapse that protrudes from the vulva (Fig S2C; Movies S2 and S3). Prolapses form by a flow of individual tumor cells and animals with tumor prolapses are motile and often shed their prolapse. In line with modulation of autophagy affecting tumor growth, inhibition of autophagy leads to an increase in the percentage of animals displaying a tumor prolapse both in gld-1 RNAi and mutant animals (Fig S2D and E)." Remark  (Figure S2E) lgg-3 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002982 lgg-3 B0336.8 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:B0336.8 B0336.8 357   III: 5697550-5697633

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0002397 tumor prolapse frequency increased Animals with a tumorous germline exhibit an increased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00049105

0 Strain