| WormBase ID | WBRNAi00107846 | Genotype | gld-1(RNAi) |
| Phenotype Remark | "(tumor cell) Invasion of the vulva region often results in the appearance of a tumor prolapse that protrudes from the vulva (Fig S2C; Movies S2 and S3). Prolapses form by a flow of individual tumor cells and animals with tumor prolapses are motile and often shed their prolapse. In line with modulation of autophagy affecting tumor growth, inhibition of autophagy leads to an increase in the percentage of animals displaying a tumor prolapse both in gld-1 RNAi and mutant animals (Fig S2D and E)." | Remark | (Figure S2D) atg-7 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00010882 | atg-7 | M7.5 | Caenorhabditis elegans |
| Identifier | Name | Description |
|---|---|---|
| WBPhenotype:0002397 | tumor prolapse frequency increased | Animals with a tumorous germline exhibit an increased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control. |
Powered by
