WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00107893 Phenotype Remark  "As expected, depletion of endogenous CYK-4 in the absence of a transgene resulted in embryonic lethality and cytokinesis failure in the first division with partial cleavage furrow ingression followed by regression. These phenotypes were rescued by wild-type CYK-4::GFP but not CYK-4GD::GFP (Figures 1E and 1F; Movie S2) even though both were expressed at similar levels (Figure 1C) and localized to the spindle midzone (data not shown)."
Remark  (Figure 1E,1F) cyk-4 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000875 cyk-4 K08E3.6 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:K08E3.6 K08E3.6 2046   III: 13768801-13769010

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0002391 cytokinesis failure Cells attempt to divide but fail to form two daughter cells.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00044595

0 Strain