WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Anatomy Term :

Definition  Neuron class of two neurons that have dual ciliated endings in the amphid sensillum; the endings are in the amphid channel, which is open to the outside. Name  ADL
Primary Identifier  WBbt:0005661

2 Children

Definition Name Synonym Primary Identifier
Amphid neuron, prob. chemosensory ADLL lineage name: ABalppppaad WBbt:0003997
Amphid neuron, prob. chemosensory ADLR lineage name: ABpraaapaad WBbt:0003995

13 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
postdauer (pheromone) Transcripts that showed significantly increased expression in ADL neurons FACS-isolated from postdauer (pheromone) one-day old adults of nrde-3(gg66) animals, comparing to ADL nuerons isolated from control nrde-3(gg66) animals. Data analysis was performed on the CLC Genomics Workbench (Qiagen) with differential expression assessed using EdgeR. WBPaper00067348:Post-dauer_upregulated_nrde-3(gg66)_ADL
  Transcripts that showed significantly decreased expression in ADL neurons of qui-1(db104) comparing to in N2 at day 1 adult stage. tximport 1.14.2 and DEseq2 1.26.0. Fold change > 2, FDR < 0.05. WBPaper00062520:qui-1(db104)_downregulated
postdauer (pheromone) Transcripts that showed significantly decreased expression in ADL neurons FACS-isolated from postdauer (pheromone) one-day old adults of N2 animals, comparing to ADL nuerons isolated from control N2 animals. Data analysis was performed on the CLC Genomics Workbench (Qiagen) with differential expression assessed using EdgeR. WBPaper00067348:Post-dauer_downregulated_N2_ADL
  Top 300 transcripts enriched in ADF, ADL, AFD, ASE, ASG, ASH, ASI, ASJ, ASK, AWA, AWB, AWC according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:Ciliated_amphid_neuron
postdauer (pheromone) Transcripts that showed significantly increased expression in ADL neurons FACS-isolated from postdauer (pheromone) one-day old adults of N2 animals, comparing to ADL nuerons isolated from control N2 animals. Data analysis was performed on the CLC Genomics Workbench (Qiagen) with differential expression assessed using EdgeR. WBPaper00067348:Post-dauer_upregulated_N2_ADL
  Transcripts that showed significantly increased expression in ADL neurons of qui-1(db104) comparing to in N2 at day 1 adult stage. tximport 1.14.2 and DEseq2 1.26.0. Fold change > 2, FDR < 0.05. WBPaper00062520:qui-1(db104)_upregulated
  Transcripts enriched in ADL according to single cell RNAseq. Genes that pass the Bonferroni threshold for multiple comparisons (q < 0.05) are significantly enriched. WBPaper00061651:ADL_enriched
postdauer (pheromone) Transcripts that showed significantly decreased expression in ADL neurons FACS-isolated from postdauer (pheromone) one-day old adults of nrde-3(gg66) animals, comparing to ADL nuerons isolated from control nrde-3(gg66) animals. Data analysis was performed on the CLC Genomics Workbench (Qiagen) with differential expression assessed using EdgeR. WBPaper00067348:Post-dauer_downregulated_nrde-3(gg66)_ADL
  Single-cell RNA-Seq cell group 91 expressed in: ADL. CellRanger, DecontX, Monocle3, Louvain algorithm. WBPaper00065623:91
  Transcripts that showed significantly altered expression in male comparing to in hermaprhodite animals in cell cluster ADL.txt. fold change > 2, FDR < 0.05 WBPaper00068349:male_upregulated_ADL.txt
  Transcripts that showed significantly altered expression in daf-2(e1370) comparing to in N2 in cell cluster ADL. fold change > 2, FDR < 0.05 WBPaper00067693:daf-2(e1370)_upregulated_ADL
  Transcripts that showed significantly altered expression in daf-2(e1370) comparing to in N2 in cell cluster ADL. fold change > 2, FDR < 0.05 WBPaper00067693:daf-2(e1370)_downregulated_ADL
  Transcripts that showed significantly altered expression in male comparing to in hermaprhodite animals in cell cluster ADL.txt. fold change > 2, FDR < 0.05 WBPaper00068349:male_downregulated_ADL.txt

0 Expression Patterns

0 Life Stages

2 Parents

Definition Name Synonym Primary Identifier
neuron of the amphid sensillum amphid neuron amphid sensory neuron WBbt:0005394
neuron that senses soluable chemicals chemosensory neuron   WBbt:0005837