WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Primary Identifier  Expr3478 Subcellular Localization  In nonirradiated wild-type (N2) animals, CeBRC-2 is diffuse and detected at very low levels in nuclei. However, after radiation treatment, germ line nuclei accumulate a large number of discrete foci concordant with DNA. No signal is detected in Cebrc-2 mutants, demonstrating that the focus formation observed in wild-type animals after radiation treatment is specific to CeBRC-2. These results imply that CeBRC-2 localizes to presumptive sites of DNA damage after radiation treatment.

0 Anatomy Terms

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00020316 brc-2 T07E3.5 Caenorhabditis elegans

0 Life Stages