1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00006537 | tbb-2 | C36E8.5 | Caenorhabditis elegans |
| Primary Identifier | Expr3452 | Remark | An interesting contrast in the behaviors of centrosomal gamma- and beta-tubulins was seen in the timing of the appearance of darkened centers. With GFP::beta-tubulin, ring profiles could be seen in prometaphase and metaphase. With anti-gamma-tubulin and GFP::gamma-tubulin, they were not seen until anaphase. This suggests that despite the presence of gamma-tubulin throughout the centrosome during spindle assembly, most recruitment and polymerization of alpha/beta-tubulin dimers occurs in the outer layers. |
| Subcellular Localization | The dynamic behavior of centrosomes seen with GFP::beta-tubulin was similar to that seen with GFP::gamma-tubulin (see Expr3451). Centrosomes recruited GFP::beta-tubulin and enlarged from prophase through metaphase. They showed ring-like profiles with darkened centers, and during anaphase to telophase, the posterior ring underwent swinging, posterior migration, flattening, and fragmentation. Two small dots of GFP::beta-tubulin, presumably the daughter centrosomes, could be seen within the expanding rings during anaphase to telophase. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00006537 | tbb-2 | C36E8.5 | Caenorhabditis elegans |
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