| Primary Identifier | Expr11895 | Subcellular Localization | CeVPS34 protein was ubiquitously present in all major tissues and at all developmental stages in C.elegans. Most interestingly, CeVPS34 was strongly concentrated at a perinuclear localization in all blastomeres of the embryo, but some weak granular and diffuse cytoplasmic anti-CeVPS34 staining was also evident. In larval and adult stages of both sexes, the protein was also found at the nuclear envelope of the cells from most major tissues such as the hypodermis or the intestine. Furthermore, we observed that CeVPS34 was abundantly present in the germline of adult hermaphrodites. Both the mitotically dividing germ line precursor nuclei and the differentiated oocytes of the more proximal germ line showed bright perinuclear and cytoplasmic staining. Altogether, these results point to the nuclear envelope and possibly the perinuclear endoplasmic reticulum (ER) as the innermost localization sites for CeVPS34. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00006932 | vps-34 | B0025.1 | Caenorhabditis elegans |
| Remark | Definition | Other Name | Public Name | Primary Identifier |
|---|---|---|---|---|
| All C. elegans development stages, including embryo, larva and adult stage. | all stages Ce | WBls:0000002 |
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