1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00018158 | comp-1 | F37E3.3 | Caenorhabditis elegans |
| Primary Identifier | Expr16181 | Subcellular Localization | The COMP-1 fusion proteins displayed a punctate pattern in the cytoplasm of both developing spermatids and mature sperm, where they were restricted to the cell body region. These punctae were visible in sperm from both males and hermaphrodites. To determine whether the COMP-1 protein was localized to a specific subcellular location, we performed co-labeling experiments with the vital dye Mitotracker, a marker of mitochondria, and PEEL-1::GFP, which labels the sperm-specific membranous organelles (MOs) (Chen et al., 2000; Seidel et al., 2011). We also examined the phosphatase GSP-3/4, which is involved in cytoskeletal dynamics and shows polarized localization within the pseudopod (Wu et al., 2011). COMP-1 did not colocalize with any of these markers of sperm structure or with the sperm nucleus, and its absence from the pseudopod suggests that it is not involved directly with cellular locomotion, at least by modulating cytoskeletal dynamics. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00018158 | comp-1 | F37E3.3 | Caenorhabditis elegans |
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