| Primary Identifier | Expr1501 | Subcellular Localization | Abundant levels of yolk receptors were detected in the oocytes of adult hermaphrodites. Very little anti-RME-2 signal is detected at the plasma membrane. Instead, RME-2 is associated with internal membrane structures, probably recycling endosomes. Concomitant with yolk accumulation during oocyte maturation, yolk receptors are redistributed from deeper portions of the cytoplasm in early oocytes to the cortical cytoplasm near the plasma membrane in the most mature oocytes. After fertilization of the oocytes, the yolk receptor protein becomes internalized again, sinking away from the plasma membrane. Clusters of gold-decorated receptors are found inside the cytoplasm of the early embryo, with very little expression at the level of the plasma membrane. The same results are obtained using an anti-RME-2 antibody directed towards the intracellular domain of the protein (INT). |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| a female haploid germ cell. | oocyte | ovum | WBbt:0006797 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004374 | rme-2 | T11F8.3 | Caenorhabditis elegans |
| Remark | Definition | Other Name | Public Name | Primary Identifier |
|---|---|---|---|---|
| The stage after an hermaphrodite animal is fully-developed and reaches maturity. | adult hermaphrodite Ce | WBls:0000057 |
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