| Pattern | In transgenic animals that overexpressed the functional RPM-1::GFP, both the anti-RPM-1 and anti-GFP antibodies gave identical patterns and showed that RPM-1::GFP was localized in distinct subcellular regions of the nervous system. Strong RPM-1::GFP expression was seen in the nerve ring and nerve cords but not in commissural processes that do not form synapses. Costained the transgenic animals with anti-SNT-1 antibodies and anti-GFP antibodies and analysis of confocal images revealed that RPM-1::GFP was localized adjacent to SNT-1 in presynaptic terminals. Coexpression of RPM-1 and SNB-1::GFP in the GABAergic DD and VD neurons specifically found that RPM-1 and SNB-1::GFP were present in nonoverlapping regions at individual GABAergic NMJs. | Primary Identifier | Expr1057 |
| Subcellular Localization | RPM-1::GFP expression was occasionally found in some neuronal cell bodies but was excluded from nuclei. |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes. | nerve ring | circumpharyngeal nerve ring | WBbt:0006749 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004457 | rpm-1 | C01B7.6 | Caenorhabditis elegans |
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