WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  let-23 expression is first observed in the early L3 larvae (1-3 h after L2 molt, 1.5-3.5 h before division of the Pn.p cells), in all six Pn.p cells and is concentrated in a lateral ring. let-23 appears to be specifically associated with the cell junction. Let-23 expression decreases rapidly in the 2o cells (P5.p and P7.p) starting at 3 h and disappearing completely by 3.5 h after L2 molt. Expression in P3.p, P4.p and P8.p decreases gradually until no longer seen 3.5-4 h after L2 molt. Expression in P6.p increases starting at 4-4.5 h after L2 molt. At this stage expression is observed in a lateral ring in the plasma membrane. At approximately 4-4.5 h after the L2 molt, expression is localized to the P6.p cell junction in 69% of the animals and staining is more punctate. In the remaining 31% of animals staining is broadly distributed on the apical plasma membrane of P6.p. Primary Identifier  Expr688
Remark  This information was extracted from published material (Archana Sharma-Oates, Andrew Mounsey and Ian A. Hope). Subcellular Localization  let-23 specifically associate with cell junctions.
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5 Anatomy Terms

Definition Name Synonym Primary Identifier
descendent cell of post-embryonic blast cell P5, posterior, in hermaphrodite. P5.p hermaphrodite   WBbt:0008121
descendent cell of post-embryonic blast cell P4, posterior, in hermaphrodite. P4.p hermaphrodite   WBbt:0008117
  P8.p hermaphrodite   WBbt:0008133
  P7.p hermaphrodite   WBbt:0008129
  P6.p hermaphrodite   WBbt:0008125

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002299 let-23 ZK1067.1 Caenorhabditis elegans

1 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035