WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Primary Identifier  Expr3800 Subcellular Localization  Dissected gonads were costained with antibodies to HIM-8 and to the NE proteins LMN-1/lamin or SUN-1/matefin. Close association between HIM-8 foci and nuclear-envelope staining is clearly evident, particularly in individual optical sections from these data sets. Fluorescence-intensity profiles confirm that HIM-8 foci are peripheral with respect to the mass of DAPI-stained chromatin and lie very close to or embedded within the nuclear lamina. Frequently, HIM-8 foci have a crescent-shaped appearance, especially in the transition zone, as if the protein localizes to a patch along the nuclear surface. In him-8(me4), the only mutant allele in which HIM-8 foci remain associated with the X PC, the protein also retains its localization at the NE.

0 Anatomy Terms

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001867 him-8 T07G12.12 Caenorhabditis elegans

0 Life Stages