| Pattern | At 2-cell embryo, MIX-1 protein can be seen in AB, but not in P1. After mitosis, MIX-1 staining becomes more diffuse and less intense, only to increase in intensity just prior to the next mitosis. This apparent oscillation in MIX-1 protein levels is obscured by the accumulation of MIX-1 protein in the interphase nuclei of embryos (~30-cell stage) undergoing rapid cell divisions. However, at a time after most embryonic cell divisions have occurred, cell cycle regulationof MIX-1 becomes noticeable once again. Mitotic cells exhibitintense MIX-1 staining, and interphase cells exhibit weaker X chromosomespecific staining. | Primary Identifier | Expr1443 |
| Remark | No detailed description on cellular expression pattern at later stages. mix-1 is previously known as let-29. | Subcellular Localization | In young embryos, prior to the initiation of dosage compensation (30 cells), MIX-1 is localized to all chromosomes during mitosis. In older wild-type XX embryos that have activated dosage compensation, MIX-1 is localized to X in interphase cells; it then appears to accumulate to a higher level in mitotic cells, where it associates with all chromosomes. |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| Embryonic founder cell | AB | AB blastomere | WBbt:0004015 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00003367 | mix-1 | M106.1 | Caenorhabditis elegans |
| Remark | Definition | Other Name | Public Name | Primary Identifier |
|---|---|---|---|---|
| The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. | embryo Ce | WBls:0000003 |
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