| Pattern | To determine whether the APC might function at GABA synapses, we analyzed the subcellular localization of a GFP-tagged APC subunit EMB-27 CDC16 (GFP::EMB-27) relative to mCherry-tagged SNB-1 Synaptobrevin (mCherry::SNB-1), which marks presynaptic sites, in GABA neurons (Fig. 7A). We found that approximately 90% of the GFP::EMB-27 puncta co-localized with mCherry::SNB-1 puncta (90.28 ± 14.11%, n = 20 animals) and vice versa (90.11 ± 15.67%, n = 20 animals). | Primary Identifier | Expr11438 |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| neuron that uses GABA as a vesicular neurotransmitter. | GABAergic neuron | WBbt:0005190 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00001281 | emb-27 | F10B5.6 | Caenorhabditis elegans |
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