| Pattern | Transgenic animals containing the fos-1a::YFP-TX and -TL reporters showed the same expression pattern at all times examined, and fos-1a::YFP-TL protein localized to the nucleus. fos-1a::YFP-TL also rescued the AC-invasion defect when expressed in fos-1(ar105) mutants. fos-1a was expressed at the highest level in the AC and at lower levels in neighboring somatic gonad cells during AC invasion. No expression of fos-1a was detected in vulval cells. In contrast, both the fos-1b::CFP-TX and -TL reporters directed expression in vulval cells and the AC. fos-1b::CFP-TL also drove expression in neighboring uterine cells, whereas fos-1b::CFP-TX did not, suggesting the presence of a downstream uterine enhancer element in fos-1b::CFP-TL. Unlike fos-1a expression, levels of fos-1b::CFP-TL protein were not greater in the AC compared to neighboring cells. Moreover, whereas the fos-1a reporters drove expression almost exclusively in the somatic gonad cells, the fos-1b reporters directed expression in nearly all cells at the L3 stage. | Primary Identifier | Expr3686 |
| Subcellular Localization | fos-1a::YFP-TL protein localized to the nucleus |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| anchor cell, induces vulva, part of hermaphrodite gonad. | anchor cell | AC | WBbt:0004522 |
| organ producing either sperm or ova. | gonad | WBbt:0005175 | |
| Constituent cell of a hermaphrodite vulva. | vulval cell | vulval epithelial cell | WBbt:0007831 |
| cell of the epithelia of uterus. | uterine epithelial cell | WBbt:0008435 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00001345 | fos-1 | F29G9.4 | Caenorhabditis elegans |
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