WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  In worms, SAS-4 colocalized with gamma-tubulin to centrosomes both in sperm and in the syncytial part of the gonad. SAS-4 staining in the gonad disappeared as the meiotic nuclei cellularized to form oocytes, presumably marking the point at which the centrioles are lost during oogenesis. Primary Identifier  Expr2459
Subcellular Localization  In newly fertilized embryos, SAS-4 is localized to a discrete spot near the sperm-derived pronucleus. At a slightly later stage, gamma-tubulin is recruited to the sperm centrioles forming a focus that colocalizes with SAS-4. As the embryo proceeds into mitosis, the amount of gamma-tubulin at centrosomes dramatically increases. In contrast, the SAS-4 staining remains unchanged as a small dot in the center of the centrosome.
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2 Anatomy Terms

Definition Name Synonym Primary Identifier
Male haploid germ cell. sperm spermatozoa WBbt:0006798
organ producing either sperm or ova. gonad   WBbt:0005175

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004726 sas-4 F10E9.8 Caenorhabditis elegans

2 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. embryo Ce WBls:0000003