WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  Staining is first detected after fertilization in both the oocyte and sperm pronuclei shortly before the first mitotic division. After the first cleavage, the nuclei of both AB and P1 blastomeres appear to contain equivalent levels of the protein. During the first embryonic cell cycle, the protein appears to accumulate to much higher levels in the nucleus of P1 than in the AB nucleus. As AB and P1 enter mitosis, the protein is distributed throughout the cytoplasm. After the nuclei of the AB daughters re-form, both appear to have equivalent levels of the protein and similarly with the P1 daughters but at a much higher level.. During the second cell cycle the level of the protein increases in the nuclei of both P1 daughters. Late in the cell cycle the level of protein begins to decrease in both P1 daughters and in both AB daughters and in many embryos the two AB daughters have no detectable protein. After the third cleavage (8-cell stage), there is no detectable protein in any of the AB granddaughters but staining is detected throughout the P1 granddaughters. By the 12-cell stage, there is no staining in any blastomere. Peak levels of SKN-1 detected at 4-cell stage in EMS and P2. Little or no expression are detected in ABa and ABp. Primary Identifier  Expr699
Remark  This information was extracted from published material (Archana Sharma-Oates, Andrew Mounsey and Ian A. Hope).
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9 Anatomy Terms

Definition Name Synonym Primary Identifier
Embryonic founder cell MS lineage name: P0.paa WBbt:0004458
Embryonic founder cell E lineage name: P0.pap WBbt:0004804
embryonic founder cell Psub3 lineage name: P0.ppp WBbt:0006875
embryonic founder cell Psub1 lineage name: P0.p WBbt:0006874
embryonic founder cell Psub2 lineage name: P0.pp WBbt:0006873
embryonic cell EMS   WBbt:0006876
embryonic cell ABa   WBbt:0005906
embryonic cell ABp   WBbt:0005994
Embryonic founder cell AB AB blastomere WBbt:0004015

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004804 skn-1 T19E7.2 Caenorhabditis elegans

1 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The C. elegans life stage spanning 0-100min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 28 cells. From first cleavage until the start of gastrulation. blastula embryo Ce WBls:0000005