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WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  In addition to its localization in the sarcoplasmic reticulum and the ER of the hypodermis, RNF-121 expressed in the ER membrane of the seam cells (specialized epithelial cells), vulva, uterus, spermatheca, sheath cells and distal tip cells (DTCs), based on the typical pattern of intracellular reticular network in these tissues. Primary Identifier  Expr9016
Remark  Picture: Fig 1. Subcellular Localization  The RNF-121::GFP transgene is expressed in intracellular reticular structures as well as in the perinuclear region, suggesting its localization to the ER. ER membrane localization was confirmed by co-localization with the mRFP::SP12 ER reporter (12-kDa signal peptidase subunit). SP12 has been shown to be enriched in the rough ER membrane, however in C. elegans neurons it is expressed throughout the ER membrane, both in the cell body and neurites. Expression of RNF-121::GFP is also detected in scattered dots that are co-localized with the Golgi reporter alpha-mannosidase II.
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10 Anatomy Terms

Definition Name Synonym Primary Identifier
female genital. vulva   WBbt:0006748
an accordion-like tube that contains sperm and is the site of oocyte fertilization. spermatheca   WBbt:0005319
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion. body wall musculature body muscle WBbt:0005813
Epidermal layer. hypodermis epidermis WBbt:0005733
Posterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad posterior distal tip cell gon herm dtc P WBbt:0004506
Anterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad anterior distal tip cell gon herm dtc A WBbt:0004520
The organ in which the eggs are developed and protected until laid. uterus   WBbt:0006760
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail seam cell lateral hypodermis WBbt:0005753
five pairs of thin gonadal sheath cells form a single layer covering the germ line component of each arm, each pair occupying a stereotyped position along the gonad proximal-distal axis. gonadal sheath cell   WBbt:0005828
The components of the gonad that are separate from the germline proper. In hermaphrodite, these include five tissues which are all derived from the somatic primordium : the distal tip cells, the gonadal sheath, the spermatheca, the spermatheca-uterine valve (sp-ut) and the uterus. somatic gonad somatic germline WBbt:0005785

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00007626 rnf-121 C16C10.5 Caenorhabditis elegans

0 Life Stages