WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  NEG-1::GFP is asymmetrically localized in the early embryo. NEG-1::GFP was detected in the zygotic nucleus and at equal levels in both nuclei of the two-cell embryo (23 of 23). However, at the four-cell stage, NEG-1::GFP expression was markedly higher in nuclei of the anterior AB blastomeres than in the nuclei of EMS and P2 (31 of 34). Following the four-cell stage, NEG-1::GFP remained high in the granddaughters of the AB blastomere and diminished progressively in subsequent divisions (data not shown). In the adult germline, NEG- 1::GFP was observed in the nuclei of distal germ cells and the nuclei of growing oocytes except for the most proximal oocyte. Moreover, intense sub-nuclear localization of NEG-1:GFP was observed on condensed chromatin. Primary Identifier  Expr12428
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6 Anatomy Terms

Definition Name Synonym Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes. germ line germline WBbt:0005784
embryonic founder cell Psub1 lineage name: P0.p WBbt:0006874
embryonic cell ABa   WBbt:0005906
embryonic cell ABp   WBbt:0005994
Embryonic founder cell AB AB blastomere WBbt:0004015
A cell that is the AB blast cell or is a lineal descendant of AB. AB lineage cell   WBbt:0008611

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00017985 neg-1 F32D1.6 Caenorhabditis elegans

3 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The C. elegans life stage spanning 0-20min after first cleavage at 20 Centigrade. Contains 2 cells. 2-cell embryo Ce WBls:0000007
  The C. elegans life stage spanning 20-40min after first cleavage at 20 Centigrade. Contains 4 cells. 4-cell embryo Ce WBls:0000008