WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  MET-2 was visualized with several reagents, including anti-MET-2 antibody, epitope-tagged transgene generated by mosI-mediated single copy insertion (mosSCI), and endogenously-tagged MET-2 generated by CRISPR-Cas9 editing. These reagents detected nuclear MET-2 throughout the germ line. We observed MET-2 puncta superimposed on a more diffuse signal in germline nuclei and, to a lesser extent, cytoplasm in both male and hermaphrodite germ lines. The MET-2 distribution appeared to shift as germ cells moved from the proliferative region into and through meiosis; nuclear puncta were more obvious in mitotic and leptotene-zygotene nuclei, and the signal became more evenly distributed as nuclei entered and progressed through pachytene stage. We conclude that germline MET-2 comprises nuclear and cytoplasmic pools. Primary Identifier  Expr14304
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3 Anatomy Terms

Definition Name Synonym Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes. germ line germline WBbt:0005784
Gonochoristic organism that can produce male gametes. male male organism WBbt:0007850
Multi-cellular organism that can produce both male and female gametes. hermaphrodite hermaphroditic organism WBbt:0007849

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00019883 met-2 R05D3.11 Caenorhabditis elegans

0 Life Stages