WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  TLK-1 protein was exclusively found in nuclei from the 2-cell stage until morphogenesis. TLK-1 was also detectable in adult germline nuclei, suggesting that the TLK-1 protein is maternally expressed. Primary Identifier  Expr2758
Remark  Staining was completely eliminated in tlk-1(RNAi) embryos and entirely competed by preincubation of TLK-1 antisera with MBP-TLK-1. Subcellular Localization  Examination of TLK-1 immunostaining with respect to the cell cycle revealed that TLK-1 was highly expressed in interphase and prophase nuclei. TLK-1 immunostaining diminished dramatically upon nuclear envelope break-down and did not appear to be above background levels in mitotic cells from metaphase through telophase. However, it is impossible to distinguish whether this is due to diffusion of nuclear TLK-1 or due to degradation of the TLK-1 protein during mitosis.
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1 Anatomy Terms

Definition Name Synonym Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes. germ line germline WBbt:0005784

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006579 tlk-1 C07A9.3 Caenorhabditis elegans

2 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. embryo Ce WBls:0000003
  The stage after an hermaphrodite animal is fully-developed and reaches maturity. adult hermaphrodite Ce WBls:0000057