WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  ftn-1::gfp is specifically expressed only in intestine from embryo to adult stages. In ftn-1::gfp transformed worms, GFP expression was observed as bright spots, which could be distinguished from auto fluorescent gut granules. The spots were concentrated in the proximal region of intestine (pharyngeal intestinal valve) and in the distal part of intestine (proctodeum). Primary Identifier  Expr3080
Remark  Gene Regulation: When ftn-1::gfp worms were transferred on FAC containing plates, the intensity of GFP spots was dramatically increased and the spots were spread throughout the whole intestine. Thus, ftn-1::gfp expression was induced by iron treatment in C. elegans. The level of GFP expression was consistently different between ftn-1::gfp and ftn-2::gfp transformed animals. Although a slight variation was observed among transformed animals, it appeared that GFP expression level was relatively lower in ftn-1::gfp animals than in ftn-2::gfp.
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2 Anatomy Terms

Definition Name Synonym Primary Identifier
A group of six equivalent cells forms a tightly constructed `valve` that links the posterior bulb of the pharynx to the anterior four cells of the intestine. These six cells comprise a small epithelial channel with a cuticular lining in continuity with the pharyngeal cuticle and link the lumen of the pharynx to the large lumen of the anterior intestine. pharyngeal-intestinal valve cardia WBbt:0005767
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages. intestine gut WBbt:0005772

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001500 ftn-1 C54F6.14 Caenorhabditis elegans

0 Life Stages