WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  LIN-12 expression is first detected at very low, but above background, levels in each of the cells in the E4 intestinal primordium. By the E8 stage, LIN-12 appears most abundant in cells in the right half of the primordium, and is present at lower or undetectable levels in cells in the left half. The left-right asymmetry in LIN-12 expression persists to the E16 stage, when dynamic changes in LIN-12 expression occur along the anterior-posterior axis of the primordium. At the E16 stage, LIN-12 is prominent in punctate structures near the midline of the primordium; these structures resemble in shape, position and timing of appearance the 'apical vesicles' described in an ultrastructural study of the primordium. Primary Identifier  Expr1040
Remark  Authors only analyzed the expression pattern of LIN-12 before and during intestinal twist. The patterns describe are not observed in embryos from lin-12(n941) hermaphrodites or from lin-12(RNAi) hermaphrodites, and are thus specific for LIN-12.
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1 Anatomy Terms

Definition Name Synonym Primary Identifier
any of 20 large epithelial cells which form a tube and are mostly situated as bilaterally symmetric pairs around the tubular lumen. Each of these cell pairs forms an intestinal ring ( II-IX int rings). The most anterior intestinal ring (int ring I), however, is made of four cells. Intestinal cells contain large nuclei with large nucleoli and numerous autofluorescent granules in their cytoplasm. intestinal cell   WBbt:0005792

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003001 lin-12 R107.8 Caenorhabditis elegans

1 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The C. elegans life stage spanning 420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo. 1.5-fold embryo Ce WBls:0000018