WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Anatomy Term :

Definition  Male specific interneuron, project into preanal ganglion Name  CP9
Primary Identifier  WBbt:0004887 Synonym  lineage name: P11.aapp

1 Children

Definition Name Synonym Primary Identifier
nucleus of pedigree P11.aapp P11.aapp nucleus   WBbt:0001908

2 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly altered expression in male comparing to in hermaprhodite animals in cell cluster CP9.txt. fold change > 2, FDR < 0.05 WBPaper00068349:male_downregulated_CP9.txt
  Transcripts that showed significantly altered expression in male comparing to in hermaprhodite animals in cell cluster CP9.txt. fold change > 2, FDR < 0.05 WBPaper00068349:male_upregulated_CP9.txt

9 Expression Patterns

Remark Reporter Gene Primary Identifier Pattern Subcellular Localization
    Expr3013 Expressed in AVH/AVJ, BAG, PDA, PVR, SAA, SDQ, SMB. Faint or variable expression observed in BDU. Male specific expression in Rays 1, 4, 5, 7, CP9.  
    Expr15433    
    Expr3010 Expressed in AUA, PVM, URX. Faint or variable expression observed in RMG, ADA, and an extra pair of cells in the head. Male specific expression in CP9.  
No detailed description on cellular expression pattern at hermaphrodites.   Expr1300 LIN-29 accumulates in B cell progeny. In contrast to the LIN-29 accumulation pattern observed in wild-type hermaphrodites, LIN-29 is not detectable in the F, U, Y, or M blast cell nuclei, or in their progeny, in males. LIN-29 is detected in the progeny of B. LIN-29 is first detectable in B cell progeny during the L3 stage. Although all B.a and B.p progeny accumulate LIN-29, the LIN-29 accumulation signals appear weaker and transient in B.p progeny. The identification of these LIN-29-accumulating cells as B progeny is based on their size, shape, and relative position within the male tail and is further supported by laser microsurgery experiments and the examination of LIN-29-accumulation patterns in a mutant with defects in B cell specification. Elimination of the B cell by laser micro-surgery during the L1 stage reduced the number of LIN-29-accumulating nuclei in the male tail by 1015. LIN-29 appears to persist in B.a progeny in the adult stage. LIN-29 accumulates in the linker cell. The first male-specific LIN-29 accumulation is detected in the nucleus of the linker cell (LC) positioned at the tip of the growing end of the gonad. LIN-29 accumulates in the LC during the L3 stage, after the gonad arm has completed the 180 turn. LIN-29 remains detectable until the late L4 stage when its disappearance is presumably due to LC destruction. LIN-29 accumulates in the male tail seam. LIN-29 accumulates in the lateral body seam cell nuclei and in the SET nuclei in L4 stage wild-type males. LIN-29 accumulates in ventral cord nuclei. During the late L3 stage, five to seven nuclei that belong to the preanal ganglion accumulate LIN-29. Four preanal ganglion nuclei accumulates LIN-29 and were identified by position as the CA9, CP9, AS11, and VA11 neurons which are descended from P11.a. LIN-29 accumulation in the preanal ganglion cluster persists through adulthood. In late L4 stage and adult males, additional ventral cord nuclei anterior to the preanal ganglion accumulate LIN-29. The accumulation of LIN-29 in ventral cord neurons is not observed in hermaphrodites. Also in contrast to hermaphrodites, the ventral hypodermal nuclei positioned within the ventral cord do not contain detectable levels of LIN-29 in adult males. nuclei
Picture: Figs. 1A and B.   Expr8357 unc-55 expression was observed in the spicule protractor and retractor muscles and in the male-specific neuron CP9. Punc-55::gfp adult males were fixed and stained with phalloidin-tagged rhodamine and partial colocalization between the muscle stain and the Punc-55::gfp was observed.  
    Expr12670 egl-8 is expressed in the vas deferens, spicule protractor muscles, diagonal muscles and a male-specific neuron that is probably CP8 or CP9 and is also widely expressed in the nervous system, as expected from previous work (Lackner et al., 1999; Miller et al., 1999).  
    Expr3005 Expressed in IL1 and PQR. Male specific expression in SP and CP9.  
    Expr3702 Expression in male-specific structures is directed by all three promoters. Promoter pA directs expression in the spicule protractor muscles of the proctodeum and in a single male-specific neuron that is likely to be CP8 or CP9. Promoter pB directs expression in the spicule retractor muscles, gubernaculum retractor muscles, posterior oblique muscles, diagonal muscles, and the vas deferens. Promoter pC also directs expression in the vas deferens, as well as the seminal vesicle and the valve that separates the seminal vesicle and vas deferens. Thus itr-1 is expressed widely in the sex-associated muscles and somatic gonad of males.  
    Expr15350    

0 Life Stages

2 Parents

Definition Name Synonym Primary Identifier
Neuron class of nine male-specific neurons with cell body in ventral cord and preanal ganglion CP neuron   WBbt:0005310
post-embryonic cell of pedigree P11.aap in male. P11.aap male   WBbt:0008107