WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Primary Identifier  Expr8837 Remark  Picture: Figure 4B, 4C, Figure S6
Subcellular Localization  EGG-4/5 localize to the cortex of oocytes. In addition, EGG-4/5 were also detected in oocyte nuclei. The cortical and nuclear signals were eliminated by RNAi codepletion of EGG-4 and EGG-5, confirming that they correspond to endogenous EGG-4/5. Staining of hermaphrodites homozygous for single deletions in either EGG-4 or EGG-5 gave the same pattern as wild-type, confirming that EGG-4 and EGG-5 are both expressed in oocytes. In zygotes in meiosis II, EGG-4/5 were enriched on subcortical puncta, also positive for EGG-3. EGG-3-positive puncta invade the cytoplasm during meiosis II. EGG-4/5 puncta, in contrast, were prominent only near the cortex and around the sperm pronucleus. No EGG-4/5 were detected above background in 2-cell embryos.

1 Anatomy Terms

Definition Name Synonym Primary Identifier
a female haploid germ cell. oocyte ovum WBbt:0006797

2 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00020035 egg-5 R12E2.10 Caenorhabditis elegans
WBGene00020652 egg-4 T21E3.1 Caenorhabditis elegans

0 Life Stages