| Pattern | tmc-1 is expressed in the high-threshold mechanosensor, ALA. Previous research has identified C. elegans tmc-1 gene to be expressed in different tissues such as the body wall muscles and neuronal tissue including sensory neurons, cholinergic ventral cord neurons, and pharyngeal neurons (Chatzigeorgiou et al., 2013; Kratsios et al., 2011; Tang et al., 2020; Zhang et al., 2015). To further investigate the role of TMC-1 in mechanosensory neurons, we firstly generated a new transcriptional reporter line for the endogenous C. elegans tmc-1 promoter (4kb upstream of the start of the tmc-1 gene) driving the red fluorescent protein mKate2 (ljEx1221 [Ptmc-1(4kb)::mKate2]). We confirmed previous results that tmc-1 is expressed in ALA (Zhang et al., 2015) using a reporter strain carrying an ALA neuron marker (ljEx463 [Pida-1::GFP]). | Primary Identifier | Expr15539 |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| Neuron class of one neuron, sends processes laterally and along dorsal cord. | ALA | lineage name: ABalapppaaa | WBbt:0003955 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00020490 | tmc-1 | T13G4.3 | Caenorhabditis elegans |
Powered by
