WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  In five independent reporter lines generated, fluorescence was regularly observed in the ALA interneuron. In addition, variable reporter expression was observed in cholinergic motor neurons in the ventral nerve cord but not in GABA motor neurons of the ventral nerve cord. Rather, the vav-1 reporter was expressed in two GABA motor neurons in the head, known as RME dorsal and RME ventral, which regulate head oscillations. Several cell types were found to be negative for vav-1 reporter expression. The tested vav-1 reporters did not show co-expression with markers of dopaminergic neurons (Pdat-1::GFP), command interneurons of the locomotory circuit, which directly activate motor neurons (Pglr-1::RFP) or with a marker of a small set of sensory neurons (AWC and ASE neurons, marked by Pceh-36::RFP). In sum, fluorescent vav-1 reporters are expressed in a small subset of neurons that comprise multiple cell types, including an interneuron, cholinergic motor neurons and a small subset of GABAergic motor neurons. Primary Identifier  Expr12083
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4 Anatomy Terms

Definition Name Synonym Primary Identifier
Neuron class of one neuron, sends processes laterally and along dorsal cord. ALA lineage name: ABalapppaaa WBbt:0003955
neuron that uses vesicular acetylcholine as a neurotransmitter. cholinergic neuron ACh neuron WBbt:0006840
Ring motor neuron RMED lineage name: ABalapppaap WBbt:0005027
Ring motor neuron RMEV lineage name: ABplpappaaa WBbt:0005021

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006887 vav-1 C35B8.2 Caenorhabditis elegans

0 Life Stages