WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Primary Identifier  Expr3067 Subcellular Localization  Anti-GPA-5 antibodies were detected not only in the cilia, but also in the cell bodies and axons of the AWA neurons. Often, although faintly, staining was observed in the ADL cell bodies, but not in the ASI cells. A punctate staining pattern of the axon with anti-GPA-5 antibodies suggested that GPA-5 might be located at the synaptic sites of the AWA axons. Therefore, animals that expressed a snb-1::GFP fusion construct specifically in AWA was generated. Due to its fusion with SNB-1 synaptobrevin, green fluorescent protein (GFP) localizes to synaptic vesicles in these animals. Staining with anti-GPA-5 serum showed a punctate localization of GPA-5 close to SNB-1::GFP, suggesting that GPA-5 might function at the periactive zones of the AWA synapses.
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4 Anatomy Terms

Definition Name Synonym Primary Identifier
Amphid neuron, prob. chemosensory ADLL lineage name: ABalppppaad WBbt:0003997
Amphid neuron, prob. chemosensory ADLR lineage name: ABpraaapaad WBbt:0003995
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath AWAL lineage name: ABplaapapaa WBbt:0003831
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath AWAR lineage name: ABpraapapaa WBbt:0003830

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001667 gpa-5 F53B1.7 Caenorhabditis elegans

0 Life Stages