WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  Transgenic embryos carrying a 3x28 bp tandem repeat in an otherwise promoter-less GFP reporter, showed expression in a pair of head neurons with dendrites extending to the tip of the head, consistent with ASJ morphology and position. However, once the embryo hatched, the number of animals with GFP-fluorescent ASJ neurons decreased dramatically. Very few L1 larvae showed expression in ASJ, but none in L2-L4 larvae or adult animals. This is most likely due to the requirement of additional cis-regulatory regions in the surrounding promoter area necessary for post-embryonic maintenance of trx-1 expression. A bipartite motif, within the trx-1 promoter, composed of two 6 bp elements (CAACCC and AATTAA), separated by a 3 bp linker, is absolutely required for ASJ expression. Hence, mutation of either of the two individual 6 bp elements resulted in the abolishment of GFP expression in ASJ neurons, while mutation of the 3 bp linker did not disrupt GFP expression. Primary Identifier  Expr12270
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2 Anatomy Terms

Definition Name Synonym Primary Identifier
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil ASJL lineage name: ABalpppppppa WBbt:0003886
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil ASJR lineage name: ABpraaappppa WBbt:0003885

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00015062 trx-1 B0228.5 Caenorhabditis elegans

1 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. embryo Ce WBls:0000003