WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  To investigate whether shorter twk-40 promoters might exhibit neuronal specificity, we examined an upstream portion (Ptwk-40L, 2.5 kb, upstream of twk-40b first exon) and a downstream portion (Ptwk-40R, 2.8 kb, upstream of twk-40a first exon, including the first exon of twk-40c) of the Ptwk-40F promoter. A Ptwk-40L::GFP reporter and a Ptwk-40R:: mCherry reporter both labeled C. elegans head neurons, the ventral nerve cord, and tail neurons. However, it appeared that Ptwk-40R::mCherry also labeled motor neurons while Ptwk-40L::GFP did not. We next crossed the two transgenes into same animals. In these animals, we failed to identify head neurons obviously co-labeled by the two reporters. Interestingly, an unidentified tail neuron at the position of DVA/DVB/DVC was co-labeled. Consistently, multiple motor neurons were labeled by Ptwk-40R::mCherry but not by Ptwk- 40L::GFP. Consistent with our earlier results, Ptwk- 40L::GFP and Pnmr-1::mCherry appeared to co-label AVA, AVE and AVG neurons. Primary Identifier  Expr16594
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8 Anatomy Terms

Definition Name Synonym Primary Identifier
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring. ventral nerve cord ventral cord WBbt:0005829
neuron with its cell body situated in the head, excluding the pharynx. head neuron   WBbt:0006751
neuron with its cell body situated in the tail, posterior to rectum. tail neuron   WBbt:0006759
Ventral cord interneuron, synapses onto VA, DA, and AS motor neurons; formerly called alpha AVAL lineage name: ABalppaaapa WBbt:0003870
Ventral cord interneuron, synapses onto VA, DA, and AS motor neurons; formerly called alpha AVAR lineage name: ABalaappapa WBbt:0003869
Neuron class of one ventral cord interneuron, few synapses. AVG lineage name: ABprpapppap WBbt:0003850
Ventral cord interneuron, like AVD but outputs restricted to anterior cord. AVEL lineage name: ABalpppaaaa WBbt:0003864
Ventral cord interneuron, like AVD but outputs restricted to anterior cord. AVER lineage name: ABpraaaaaaa WBbt:0003863

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006691 twk-40 T28A8.1 Caenorhabditis elegans

0 Life Stages