WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  All four anti-Lpin-1 antibodies detected a protein at the expected size in N2 embryonic extract that was reduced in lpin-1(RNAi) embryos to ~25% of the wild-type amount. Primary Identifier  Expr8650
Remark  Picture: Fig S1, Fig 1. Subcellular Localization  To determine the subcellular localization of Lpin-1, control(RNAi) and lpin-1(RNAi) embryos expressing GFP-fused signal peptidase SP-12 (GFPSP-12) were immunostained with all four anti-Lpin-1 antibodies. Anti-Lpin-1 (4FRP and 4FFA) antibodies showed that the soluble Lpin-1 was localized weakly throughout the cytoplasm and nucleoplasm and was enriched in the ER, where it colocalized with GFPSP-12. The anti-Lpin-1 (4FMI and 4FLZ) antibodies showed similar staining but, in addition, showed an enrichment of signal in the NE compared with the ER.

0 Anatomy Terms

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00010425 lpin-1 H37A05.1 Caenorhabditis elegans

0 Life Stages