WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  In the tmem-135 promoter::GFP-expressing strain, as well as in the eight independent TMEM-135::GFP-expressing strains, ubiquitous expression from the pretzel embryo to the adult stage was observed, despite mozaicism due to the extra-chromosomal array. More specifically, tmem-135 expression was more strongly expressed in the lower intestine and in the pharynx. TMEM- 135::GFP showed a high level of expression throughout the entire length of the intestine, as well as in all epithelia. Primary Identifier  Expr9176
Subcellular Localization  The lipophilic dyes Nile Red and Mitotracker Red were used to assess the co-localization of TMEM-135 with fat droplets or mitochondria, respectively. No co-localization of TMEM-135::GFP and Mito- Tracker Red (mitochondrial) was observed in the worm, whereas TMEM-135::GFP and Nile Red displayed very strong colocalization. Data provide strong evidence that the TMEM135 protein is associated with fat droplets.
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3 Anatomy Terms

Definition Name Synonym Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages. intestine gut WBbt:0005772
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine. pharynx esophagus WBbt:0003681
lies within the body wall, in close relation to nervous system and excretory system. epithelial system   WBbt:0005730

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00019345 tmem-135 K02G10.3 Caenorhabditis elegans

6 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035
  The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. L2 larva Ce WBls:0000027
  The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. L4 larva Ce WBls:0000038
  The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch. L1 larva Ce WBls:0000024
  The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. embryo Ce WBls:0000003