WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  EGG-6::GFP was expressed in a subset of epithelial cells, including epidermal, vulval and rectal cells and the excretory duct and pore. EGG-6::GFP was also observed in some neurons. Expression began around the ventral enclosure stage of embryogenesis and continued through larval development, but then decreased in adulthood. Expression was absent from internal epithelia such as the gut and pharyngeal tubes. Primary Identifier  Expr9949
Subcellular Localization  In almost all epithelia where it was expressed, EGG-6::GFP appeared strongly apically enriched. In the excretory duct and pore, EGG-6::GFP lined the luminal membrane. In the epidermis, it was distributed across the apical surfaces of most dorsal and ventral epidermal cells but was observed more weakly or variably in the lateral (seam) epidermis. The fusion was not strongly enriched at apical junctions based on co-visualization with DLG-1/Discs Large::mcherry. The fusion protein partially overlapped with but did not strongly colocalize with transepidermal intermediate filaments at hemidesmosomes. The fusion was present in many large puncta, potentially representing a vesicular compartment trafficking to or from the membrane.
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6 Anatomy Terms

Definition Name Synonym Primary Identifier
female genital. vulva   WBbt:0006748
Epidermal layer. hypodermis epidermis WBbt:0005733
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses. neuron neurone WBbt:0003679
The outlet of the excretory sinus to the exterior environment through the cuticle, on the ventral side of the head, just behind the nerve ring. excretory pore pore WBbt:0005778
cell that forms the duct of the excretory system. excretory duct cell exc duct WBbt:0004540
These cells include: B, F, Y, U, K' and K. All rectal epithelial cells contain secretory membrane stacks along this region facing the lumenal cuticle and produce some portion of the cuticular lining of the rectum. These are interfacial cells that connect the alimentary system to the main body syncytium. rectal epithelial cell rectal epithelium WBbt:0008182

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00010621 egg-6 K07A12.2 Caenorhabditis elegans

3 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. embryo Ce WBls:0000003
  A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood. larva Ce WBls:0000023