| Pattern | To study UNC-119 protein localization, we generated a C-terminal GFP knock-in line using the SEC-approach (Dickinson et al., 2015) and observed GFP expression in all neurons, as previously reported (Lim et al., 1999; Maduro and Pilgrim, 1995). The GFP signal can be detected in axons (ventral nerve cord and nerve ring) as well as dendrites (amphid nerve). Strikingly, the protein is not enriched in the cell bodies, which suggests that the protein is not freely diffusing in the cytoplasm. Although expression is mainly neuronal, low levels are also present in the hypodermal seam cells. | Primary Identifier | Expr15034 |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses. | neuron | neurone | WBbt:0003679 |
| a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail | seam cell | lateral hypodermis | WBbt:0005753 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00006843 | unc-119 | M142.1 | Caenorhabditis elegans |
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