WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  Nuclear expression of VRK-1::GFP was observed in neurons and hypodermal cells in the head, VNC and tail of C. elegans larvae. Strong expression was also detected in all VPCs. At the L3 larval stage expression was highest in the primary fated vulva cell P6.p and its descendants. At L4 stage, VRK-1::GFP was expressed at equal levels in all 22 nuclei. One of the two transgenic strains showed additional but very weak VRK-1::GFP expression in some uterine cells. Expression was never observed in the AC with any of the two strains. Primary Identifier  Expr8783
Remark  Picture: Fig 3, Fig S2. Subcellular Localization  During division of VPCs, VRK-1::GFP was nuclear during interphase but relocated to the nuclear periphery immediately before cell division. During mitosis the protein was bound to chromatin.
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10 Anatomy Terms

Definition Name Synonym Primary Identifier
Epidermal layer. hypodermis epidermis WBbt:0005733
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring. ventral nerve cord ventral cord WBbt:0005829
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses. neuron neurone WBbt:0003679
descendent cell of post-embryonic blast cell P5, posterior, in hermaphrodite. P5.p hermaphrodite   WBbt:0008121
descendent cell of post-embryonic blast cell P4, posterior, in hermaphrodite. P4.p hermaphrodite   WBbt:0008117
descendent cell of post-embryonic blast cell P3, posterior in hermaphrodite. P3.p hermaphrodite   WBbt:0008112
  P8.p hermaphrodite   WBbt:0008133
  P7.p hermaphrodite   WBbt:0008129
  P6.p hermaphrodite   WBbt:0008125
toroidal epithelial cell that make up the bulk of the uterus, four cells anterior and four cells posterior to the vulva. uterine toroidal epithelial cell ut cell WBbt:0006784

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00017895 vrk-1 F28B12.3 Caenorhabditis elegans

5 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035
  The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. L2 larva Ce WBls:0000027
  The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. L4 larva Ce WBls:0000038
  The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch. L1 larva Ce WBls:0000024