WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Primary Identifier  Expr4256 Remark  This MRP-4::GFP fusion protein is at least partially functional as it reverses the suppression of cup-5(zu223) defects by mrp-4(cd8).
Subcellular Localization  MRP-4::GFP localizes to discrete compartments that partially co-localize with LysoTracker Red in developing intestinal cells. This indicates that at least some MRP-4::GFP localizes to late endocytic compartments. Some compartments stain with MRP-4::GFP but not with LysoTracker Red and may represent other endocytic compartments or cellular organelles. Conversely, some compartments stain with LysoTracker Red but not with MRP-4::GFP: these may constitute lysosomes that are devoid of MRP-4, either because MRP-4 is normally degraded in these compartments or because MRP-4 does not normally traffic to lysosomes but is transported to other organelles.

0 Anatomy Terms

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003410 mrp-4 F21G4.2 Caenorhabditis elegans

0 Life Stages