1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00003410 | mrp-4 | F21G4.2 | Caenorhabditis elegans |
| Primary Identifier | Expr4256 | Remark | This MRP-4::GFP fusion protein is at least partially functional as it reverses the suppression of cup-5(zu223) defects by mrp-4(cd8). |
| Subcellular Localization | MRP-4::GFP localizes to discrete compartments that partially co-localize with LysoTracker Red in developing intestinal cells. This indicates that at least some MRP-4::GFP localizes to late endocytic compartments. Some compartments stain with MRP-4::GFP but not with LysoTracker Red and may represent other endocytic compartments or cellular organelles. Conversely, some compartments stain with LysoTracker Red but not with MRP-4::GFP: these may constitute lysosomes that are devoid of MRP-4, either because MRP-4 is normally degraded in these compartments or because MRP-4 does not normally traffic to lysosomes but is transported to other organelles. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00003410 | mrp-4 | F21G4.2 | Caenorhabditis elegans |