WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Primary Identifier  Expr4910 Remark  Picture: Fig 7.
Subcellular Localization  An mRFP-UNC-50 fusion protein expressed in body-wall muscles displayed a punctate distribution throughout the cytoplasm of the muscle cell. This staining is typical of the Golgi apparatus in Drosophila tissues or muscle myotubes. Indeed, a similar vesicular staining pattern is obtained with the medial Golgi marker alpha-Mannosidase II. When confocal stacks were overlaid, mRFP-UNC-50 and Mannosidase II-GFP staining showed 91 +/- 3% (n=4) colocalization. By contrast, no overlap was observed between mRFP-UNC-50 and the GFP-cytochrome b5 (cb5) fusion, which is ER resident. This demonstrates that at steady state UNC-50 is mainly localized to the Golgi system in C. elegans.

0 Anatomy Terms

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006785 unc-50 T07A5.2 Caenorhabditis elegans

0 Life Stages