WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Strain :

WormBase ID  WBStrain00054974 CGC Received  2023-02-14
Genotype  plk-1(lt106[plk-1 C52V] lt108[plk-1 L115G]) III. Laboratory  CGC
Made By  WBPerson29989 Mutagen  CRISPR_Cas9
Name  OD3696 Outcrossed  x0
Remark  Analog-sensitive allele generated by CRISPR/Cas9 engineering of the endogenous plk-1 locus. Engineered mutations confer sensitivity to 1-NM-PP1 for drug inhibition of plk-1. gRNA sequences: GGACGATTTTTGGGCAAGGG & TCTCAACGTGTATATCACTT Reference: Gomez-Cavazos JS, et al. Curr Biol. 2020 Aug 17;30(16):3101-3115.e11. doi: 10.1016/j.cub.2020.05.090 PMID: 32619481. Species  Caenorhabditis elegans
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0 Alleles

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004042 plk-1 C14B9.4 Caenorhabditis elegans