WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Phenotype : WBPhenotype:0000707 pharyngeal development variant

Description  Variations in the progression of the pharynx (feeding organ) over time, from its formation to the mature structure compared to control. In C. elegans the pharynx is divided into the anterior and posterior regions. The anterior region includes the corpus (procorpus and metacorpus - first bulb) and the posterior region includes the isthmus and terminal bulb (second bulb).

20 RNAi

WormBase ID
WBRNAi00083279
WBRNAi00083281
WBRNAi00064047
WBRNAi00065547
WBRNAi00082052
WBRNAi00082051
WBRNAi00082054
WBRNAi00082053
WBRNAi00082055
WBRNAi00065070
WBRNAi00078821
WBRNAi00078820
WBRNAi00088411
WBRNAi00078823
WBRNAi00065573
WBRNAi00065574
WBRNAi00078822
WBRNAi00065575
WBRNAi00088412
WBRNAi00065579

2 RNAi Not Observed

WormBase ID
WBRNAi00065644
WBRNAi00065966

9 Children

Identifier Name Description
WBPhenotype:0001748 pharynx unattached The pharynx or pharyngeal muscle does not form a functional connection to the mouth or buccal cavity.
WBPhenotype:0001646 no pharynx Embryos fail to generate cells that exhibit pharyngeal specification.
WBPhenotype:0000115 anterior pharynx variant Any variation in the progression of the anterior portion of the pharynx over time compared to control. In C. elegans the anterior region includes the corpus (procorpus and metacorpus - first bulb).
WBPhenotype:0001920 twisted pharynx The growth of pharyngeal components occurs in a radial fashion around the longitudinal axis of the worm as demonstrated by bent radial contractile arrays within the pharyngeal muscle cells. The defect is more pronounced as development progresses resulting in a more obvious twisting phenotype. Depending on the allele, the twist can be right-handed or left-handed
WBPhenotype:0001635 excess pharyngeal cells Animals contain an excess number of pharyngeal cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate.
WBPhenotype:0000490 pharynx disorganized The components of the feeding organ fail to be arranged in the same manner as control animals.
WBPhenotype:0001914 fewer pharyngeal cells Animals contain fewer pharyngeal cells compared to control animals. In C. elegans, pharyngeal cells are derived from MS-blastomere.
WBPhenotype:0000814 marginal cell development variant Any variation in the progression of a marginal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A marginal cell is a pharyngeal cell that connects the basement membrane to the apices of the triangle-shaped pharyngeal lumen.
WBPhenotype:0001647 posterior pharynx variant Any variation in the progression of the posterior portion of the pharynx over time compared to control. In C. elegans the posterior region includes the isthmus and terminal bulb (second bulb).

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Parents

Identifier Name Description
WBPhenotype:0000617 alimentary system development variant Any variation in the progression of the alimentary system over time, from its formation to its mature state compared to control. The alimentary system includes all the body structures involved in preparing food for absorption into the body and excretion of waste products.

14 Phenotype Allele

Public Name
qa4900
tm710
ok556
cc8266
it55
ok1465
n2820
mn63
n2825
cu8
e2286
e2123
t1002
t1001

13 Phenotype Allele Not Observed

Public Name
cn30
ij48
n2819
n2823
n3037
n2826
n2822
n3039
n2827
n2839
n2844
n2845
ak41

1 Synonyms

Name Type
pharyngeal development abnormal